The concentration of wildlife in this Park is one of the most intense in Africa. The appearance of the 9050 square kilometers varies throughout the seasons from bare bushveld in winter to a lush wonderland in the summer months. Over 400 bird species and approximately 60 mammal species make the day and night game drives and walking safaris offered in the Park an amazing experience. Thornicroft's giraffe are unique to the Luangwa Valley and some of the bird species that may be seen here include crowned crane, steppe eagle, open-billed stork, goliath heron and beautiful swallow and bee-eater species.

Wildlife viewing is best between April and October, during the dry season when animals are drawn to more permanent water sources. Most of the Park's roads are inaccessible from November to April.